Showing posts with label South Ethiopia. Show all posts
Showing posts with label South Ethiopia. Show all posts

Tuesday, 3 February 2026

Ethiopian Marburg Virus outbreak officially declared to have ended.

An outbreak of Marburg Virus in southern Ethiopia has been officially declared over, according to a press release issued by the World Health Organization on 26 January 2026. The epidemic was declared over following two consecutive incubation periods passing without any new cases being recorded (the incubation period for Marburg Virus is considered to be 21 days). Nineteen people are believed to have been infected during the outbreak, including fourteen who were confirmed to have the Virus by laboratory testing (nine of whom died), and five people who died of a disease consistent with Marburg Virus infection, and were buried by local communities before being tested. A total of 3800 people from the were tested for the Virus, with 857 people from the South Ethiopia and Sidama regions known to have come into contact with at least one victim additionally monitored for symptoms for 21 days. The epidemic was declared to have ended 42 days of the death of the last detected patient on 14 December 2025.

The outbreak was first detected on 23 October 2025 when an adult patient presented at the Jinka General Hospital with symptoms including vomiting, loss of appetite, and abdominal cramps. Nineteen confirmed and probably cases were subsequently reported in the Jinka, Malle and Dasench woredas (districts) of South Ethiopia Region, and the Hawassa Woreda in Sidama Region.

Map of woredas (districts) reporting confirmed and probable Marburg Virus disease cases in Ethiopia, as of 25 January 2026. World Health Organization.

Marburg Virus Disease is a haemorrhagic fever, similar to the closely related Ebola Virus Disease. Both are caused by single-strand negative-sense RNA viruses of the Filoviridae family. Both are easily spread though contact with bodily fluids, and can also spread by contaminated clothing and bedding.

Negative stained transmission electron micrograph of a number of filamentous Marburg Virions, which had been cultured on Vero cell cultures, and purified on sucrose, rate-zonal gradients. Erskine Palmer/Russell Regnery/Centers for Disease Control and Prevention/Wikimedia Commons.

Marburg Virus has an incubation period of between two and 21 days, manifesting at first as a high fever, combined with a severe headache and a strong sense of malaise. This is typically followed after about three days by severe abdominal pains, with watery diarrhoea and vomiting. In severe cases the disease develops to a haemorrhagic stage after five-to-seven days, manifesting as bleeding from some or all bodily orifices. This typically leads to death on day eight or nine, from severe blood loss and shock. There is currently no treatment or vaccine available for Marburg Virus, although a number of teams are working on trying to develop vaccines. 

The high rate of infection of healthcare workers seen in Marburg Virus is particularly alarming, as this tends to weaken communities ability to resist the Virus. The Virus can spread quickly in healthcare settings, infecting people whose immune systems are already stressed by other conditions, and creating aa reserve which can feed infections in the wider community. This makes it important to screen all people potentially infected with the disease as quickly as possible, and to arrange for patients to be treated in isolation, as well as quickly tracing all known contacts of any cases, and screening them for infection too.

Marburg Virus is a zoonotic infection (disease transferred from Animals to Humans), with a wild-reserve of the Virus known to be present in Egyptian Fruit Bats, Rousettus aegyptiacus, which are found across much of Africa, the Mediterranean region, the Middle East, and South Asia. These Bats form large colonies in caves or sometimes mines. They are frugivores, and can be major pests of farmed fruits, bringing them into conflict with Humans, and are sometimes hunted for food, all of which create potential avenues for the Marburg Virus to pass from a Bat host to a Human one.

A colony of Egyptian Rousette Bats, Rousettus aegyptiacus. Giovanni Mari/Flikr/iNaturalist.

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Monday, 24 November 2025

Outbreak of Marburg Virus in Ethiopia kills at least three.

At least three people have died due to infection with Marburg Virus Disease, with a further three deaths probably linked to the illness, in an outbreak in the town of Jinka in South Ethiopia, according to a press release issued by the World Health Organization on 21 November 2025. 

The Ethiopian Ministry of Health and Ethiopian Public Health Institute first raised the alarm about an outbreak of haemorrhagic fever in the town on 12 November, with the infection being confirmed as Marburg Virus by the National Reference Laboratory two days later. As of 20 November, 33 people have been tested for the Virus, with infection confirmed in six persons, three of whom have died, with the remaining three now receiving treatment. A further three people have died without testing, and are thought likely to have been infected. A total of 206 people who may have come into contact with the Virus have been identified, with an active program of contacting and testing in place.

This is the first known Human outbreak of Marburg Virus in Ethiopia, although the Virus has previously been found in Fruit Bats in the country. 

Map of Ethiopia showing location of Jinka town. World Health Organization.

Marburg Virus Disease is a haemorrhagic fever, similar to the closely related Ebola Virus Disease. Both are caused by single-strand negative-sense RNA viruses of the Filoviridae family. Both are easily spread though contact with bodily fluids, and can also spread by contaminated clothing and bedding.

Negative stained transmission electron micrograph of a number of filamentous Marburg Virions, which had been cultured on Vero cell cultures, and purified on sucrose, rate-zonal gradients. Erskine Palmer/Russell Regnery/Centers for Disease Control and Prevention/Wikimedia Commons.

Marburg Virus has an incubation period of between two and 21 days, manifesting at first as a high fever, combined with a severe headache and a strong sense of malaise. This is typically followed after about three days by severe abdominal pains, with watery diarrhoea and vomiting. In severe cases the disease develops to a haemorrhagic stage after five-to-seven days, manifesting as bleeding from some or all bodily orifices. This typically leads to death on day eight or nine, from severe blood loss and shock. There is currently no treatment or vaccine available for Marburg Virus, although a number of teams are working on trying to develop vaccines. 

Previous outbreaks of Marburg Virus have been reported in Rwanda, as well as the neighbouring Democratic Republic of Congo and Tanzania. The Virus has also been reported in a number of other African countries, including Angola, Equatorial Guinea, Ghana, Guinea, Kenya, Rwanda, South Africa, and Tanzania. The most recent outbreaks occurred in January this year in Tanzania.

The high rate of infection of healthcare workers seen in Marburg Virus is particularly alarming, as this tends to weaken communities ability to resist the Virus. The Virus can spread quickly in healthcare settings, infecting people whose immune systems are already stressed by other conditions, and creating aa reserve which can feed infections in the wider community. This makes it important to screen all people potentially infected with the disease as quickly as possible, and to arrange for patients to be treated in isolation, as well as quickly tracing all known contacts of any cases, and screening them for infection too.

Marburg Virus is a zoonotic infection (disease transferred from Animals to Humans), with a wild-reserve of the Virus known to be present in Egyptian Fruit Bats, Rousettus aegyptiacus, which are found across much of Africa, the Mediterranean region, the Middle East, and South Asia. These Bats form large colonies in caves or sometimes mines. They are frugivores, and can be major pests of farmed fruits, bringing them into conflict with Humans, and are sometimes hunted for food, all of which create potential avenues for the Marburg Virus to pass from a Bat host to a Human one.

A colony of Egyptian Rousette Bats, Rousettus aegyptiacus. Giovanni Mari/Flikr/iNaturalist.

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Thursday, 7 November 2024

Malaria in Ethiopia.

Between 1 January and 20 October 2024 more than 7.4 million cases of Malaria were reported in Ethiopia, with 1157 deaths recorded, a case fatality rate of 0.02%, according to a press release issued by the World Health Organization on 31 October 2024. On these infections, 95% were causes by Plasmodium falciparum. This is the highest number of cases reported in Ethiopia in seven years, and part of an ongoing rising trend of Plasmodium falciparum infections; in 2023, 4.21 million Malaria infections, with 527 deaths, with 70% caused by Plasmodium falciparum.

The overwhelming majority of cases occurred in the west of the country, with four regions accounting for 81% of all recorded infections and 89% of known deaths, with 44% of cases and 667 deaths in Oromo, 18% of cases and 56 deaths in Amhara, 12% of cases and 250 deaths in Southwest Ethiopia, and 7% of cases and 45 deaths in South Ethiopia. 

Geographical distribution of Malaria cases as of 20 October 2024. World Health Organization.

Of Ethiopia's 523 worodas (districts), 222 have been identified as having a high Malaria burden, together accounting for 75% of recorded Malaria cases in 2023. Fifty of these high-burden worodas are considered to be hard-to-access due to ongoing conflicts.

A slight majority of cases are males, who accounted for 56% of cases treated as outpatients and 52% of inpatient admissions. Children accounted for 16% of outpatients and 25% of inpatient admissions. This age and sex distribution is thought to be due to patterns of seasonal migration, with large numbers of adult male migrant workers seeking work in high-risk areas during the peak of the Malaria season. 

From 2000-onwards, Ethiopia had a steady reduction in the number of Malaria cases each year, driven by improved surveillance, roll-out of malaria interventions, and community health extension program. The number of cases fell to an all-time low in 2019, when only 900 000 cases were recorded, and there was no wide-ranging major epidemic, only sporadic local outbreaks. However, the country began to suffer a resurgence of the disease from 2021 onwards, with 1.3 million cases in 2021, 3.3 million cases in 2022, and 4.1 million cases in 2023. This return appears to have been driven by the Plasmodium falciparum strain of the disease, which caused 70% of the infections in 2023, and which appears to have become endemic in areas where it was not previously known.

Weekly trend of malaria cases in Ethiopia, 01 January 2021 to 13 October 2024. World Health Organization.

Malaria is caused by parasitic unicellular Eukaryotes of the genus Plasmodium, and affects a wide range of terrestrial Vertebrates. Five different species of Plasmodium can cause Malaria in Humans, with most infections caused by either Plasmodium falciparum or Plasmodium vivax, both of which are endemic to Ethiopia. The parasites are primarily spread via the bite of the female Anopheles Mosquitoes (males do not bite), but can also be spread through blood transfusions, organ transplants, or practices such as needle-sharing.

Photomicrograph of a blood smear containing a macro- and microgametocyte of the Plasmodium falciparum parasite. Both macro- and microgametocytes are products of the erythrocytic life cycle. Within a few minutes after the Anopheles sp. vector ingests the gametocytes, microgametocytes develop into microgametes, which are able to fertilize gametes. Centers for Disease Control and Prevention/Wikipedia Commons.

Malaria manifests with approximately 10-15 days after infection, as a fever, headache, and chills. Mild cases often pass soon, and can be difficult to identify as Malaria, however, more severe cases can be fatal in as little as 24 hours after the onset of symptoms. 

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