World Malaria Day is marked on 25 April each year, with the aim of raising awareness of both the disease and efforts to combat it. The day was originally adopted as Africa Malaria Day in 2001, following the signing of the Abuja Declaration at the African Summit on Malaria in 2000. This was adopted as an international observance at the 60th session of the World Health Assembly in 2007.
On World Malaria Day in 2026 the World Health Organization will be launching the campaign 'Driven to End Malaria: Now We Can. Now We Must.', which marks the fact that for the first time ever, ending Human Malaria is a genuine possibility. This includes the development of vaccines for Malaria, which are now being rolled out in 25 countries, as well as the development of genetically modified Mosquitoes which cannot spread the disease, improved Mosquito nets which are infused with dual action insecticides, seasonal chemoprevention measures which are now being offered to 54 million children in countries where Malaria is endemic, a widening of access to perennial (year round) chemoprevention, and better treatments for patients with Malaria.
Malaria is caused by parasitic unicellular Eukaryotes of the genus Plasmodium, and affects a wide range of terrestrial Vertebrates. Five different species of Plasmodium can cause Malaria in Humans, with most infections caused by either Plasmodium falciparum or Plasmodium vivax. The parasites are primarily spread via the bite of the female Anopheles Mosquitoes (males do not bite), but can also be spread through blood transfusions, organ transplants, or practices such as needle-sharing.
Malaria manifests with approximately 10-15 days after infection, as a fever, headache, and chills. Mild cases often pass soon, and can be difficult to identify as Malaria, however, more severe cases can be fatal in as little as 24 hours after the onset of symptoms.
To date, 47 countries have been declared Malaria-free, with another 46 countries reporting less than 100 000 cases of locally acquired Malaria in 2024 (the last year for which reliable figures are available). Of those 46 countries, 37 reported less than 1000 cases, 26 reported less than 100 cases, and 24 reported less than 10.
Nevertheless, the situation is not all progress; 610 000 people died as a result of Malaria in 2024, an increase on the 598 000 who died in 2023. Four countries (Eritrea, Rwanda, Tanzania, and Uganda) have reported the emergence of strains of Malaria resistant to Artemisinin, the main treatment for the disease. Furthermore, 48 countries have reported Mosquitoes developing resistance to pyrethroid insecticides, which are the most commonly used to treat Mosquito nets hung over beds. Many strains of Malaria have also emerged which lack the pfhrp2 gene, which is used in diagnostic kits, delaying treatment in many cases. The Mosquito Anopheles stephensi, which is endemic to India, has been spreading in Africa in recent years. This Mosquito caries Malaria, and is a preferential urban-dweller, placing many people at greater risk.
Another serious threat is a massive shortfall in funding for Malaria programs, with US$5.4 billion in funding (more than half the total) being cut in 2025, with the United States, the United Kingdom, Germany, France, and Japan all making significant cuts to their aid programs. This has served to underline the fragility of aid programs which are reliant on the good will of a small number of wealthy donor countries.
Malaria eradication programs have also stalled due to civil conflicts and natural disasters, with major flooding events, which often co-occur with Malaria outbreaks, becoming more common due to the warming climate.
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